Synapse Formation and Plasticity: Pre- or Post- Synaptic Mechanisms.
Li Xiaoming MD/PhD
Assistant Research Scientist
Institute of Molecular Medicine and
The human brain contains billions of neurons. They are specialized to receive and integrate a host of electrical and biochemical signals. This highly efficient communication among neurons is made possible by synapses - contacts formed between two neurons. Despite significant progress in our understanding of the anatomic structures of synapses, little is known about mechanisms of synapse formation and function, specifically, responses to pathological change.
Dr. Li received his MD and Ph.D degrees from the
Molecular Mechanism of Microbial Pathogenesis -- Structure and Function of Microbial Toxins
Sun Jianjun PhD
Department of Microbiology and Molecular Genetics
The bacterial infectious diseases are the consequences of host-pathogen interaction, and bacterial protein toxins play pivotal roles in microbial pathogenesis. Study of protein toxins is of great significances not only for prevention and treatment of infectious diseases, but also for understanding of fundamental biological processes of life. This seminar is going to present researches on Pseudomonas aeruginosa Type-III cytotoxins and anthrax toxin, with the former focusing on identification of host targets of the toxin ExoT while the latter focusing on mechanism of anthrax toxin pore formation and membrane translocation. In the end, future research directions are proposed, with an emphasis on the needs of national bio-security.
From 1991 to 1998, Dr. Jianjun Sun studied at the