报告题目：

Role of transcription factor Olig2 in the neural differentiation of stem cells

报告人：张晓东博士

时间： 2009年5月15日（星期五） 下午 2：30

地点： 独墅湖校区炳麟图书馆 7楼 720会议室

报告人简介：

Education

2005, Doctor of Philosophy

Department of Anatomical Sciences and Neurobiology

University of Louisville School of Medicine (Louisville, KY 40202)

Mentor: Dr. Fred J. Roisen

Committee: Drs. Kathleen Klueber, Mengsheng Qiu, Peter Rowell

(Associate Dean), Scott Whittemore (Chair in Kentucky Spinal

Cord Injury Research Center)

2004, Master of Science

Department of Anatomical Sciences and Neurobiology

University of Louisville School of Medicine (Louisville, KY 40202)

1993-1994, Suzhou Medical College (now part of Suzhou University)

Graduate courses study

1989, Bachelor of Science

Department of Biology, Nanjing University (Nanjing, Jiangsu, P. R. China)

Zoology, 3 scholarships received

Research Experience

2008- present: Scientist

Department of Ophthalmology and Visual Sciences

Washington University School of Medicine (St. Louis, MO 63110)

Topic: CRX and its regulatory network in retinal degenerations

2005-2008: Postdoctoral Research Associate

Department of Anatomy and Neurobiology

Washington University School of Medicine (St. Louis, MO 63110)

Topic: Olig 2 lineage cells derived from stem cells

2001-2005, Ph. D. Student

Department of Anatomical Sciences and Neurobiology

University of Louisville School of Medicine (Louisville, KY 40202)

Topic: Induction of lineage restriction and differentiation of adult human

olfactory neuroepithelial progenitors in vitro

1998-2001, Instructor

Suzhou University (Suzhou, Jiangsu, P. R. China)

Topic: Cloning and proliferation of neural stem cells from adult mouse olfactory

epithelium

1997-1998, Visiting Scientist

Department of Anatomical Sciences and Neurobiology

University of Louisville School of Medicine (Louisville, KY 40202)

Topic: Neurotrophic factors on the cells of injured adult mouse olfactory

epithelium in vitro

1994-1997, Instructor

Suzhou University (Suzhou, Jiangsu, P. R. China)

Topic: Embryonic development of Protosalanx Hyalocaranius

1989-1993, Teaching Assistant

Suzhou University (Suzhou, Jiangsu, P. R. China)

Topic: Radiation applied to the heredity and breeding in fish

Publications

Zhang X, Horrell S, Delaney D, Gottlieb D. 2008. ES Cells as a Platform for

Analyzing Neural Gene Transcription. Stem Cells. 26(7):1841-1849.

[PubMed][PDF].

Marshall CT, Lu C, Winstead W, Zhang X, Xiao M, Harding G, Klueber KM,

Roisen FJ. 2006. The therapeutic potential of human

olfactory-derived stem cells. Histology and Histopathology.

21(6): 633-643. (ISSN: 0213-3911) [PubMed][PDF]

Zhang X, Klueber KM, Guo Z, Cai J, Lu C, Winstead WI, Qiu M, Roisen FJ.

2006. Induction of neuronal differentiation of adult human olfactory

epithelial-derived progenitors. Brain Research. 1073-1074:109-119.

(Cover of the Issue) (ISSN: 0006-8993). [PubMed] [PDF]

Zhang X, Cai J, Klueber KM, Guo Z, Lu C, Winstead WI, Qiu M, Roisen FJ.

2006. Role of transcription factors in the motoneuron differentiation of

adult human olfactory epithelial-derived progenitors. Stem Cells.

24(2): 434-442. (ISSN: 1066-5099). [PubMed] [PDF]

Zhang X, Cai J, Klueber KM, Guo Z, Lu C, Qiu M, Roisen FJ. 2005. Induction

of oligodendrocytes from adult human olfactory epithelial-derived

progenitors by transcription factors. Stem Cells. 23 (3): 442-453.

[PubMed] [PDF]

Zhang X, Klueber KM, Guo Z, Lu C, Roisen FJ. 2004. Adult human olfactory

neural progenitors cultured in defined medium. Experimental Neurology.

186(2): 112-123. (Cover of the Issue) (ISSN: 0014-4886)

[PubMed] [PDF]

Zhang X, Guo Z, Zhu F, Liu N, Roisen FJ. 2001. Proliferation and self-renewal

of stem cells from the adult mouse olfactory epithelium in vitro. Chin. J.

Neurosci. 17(2): 125-128. (ISSN: 1008-0872)

Zhang X, Guo Z, Liu N, Roisen FJ. 2000. The effects of bFGF and BDNF on

the cells of injured adult mouse olfactory epithelium in vitro. Acta

Physiologica Sinica. 52(3): 193-198. (ISSN: 0371-0871) [PubMed] [PDF]