基础医学与生物科学学院院长论坛之六

报告题目：Regulation of chromosome segregation during meiosis

报告人: Hong-Guo Yu Ph.D

报告时间: 2011年5月13日（周五）上午10:00

报告地点: 苏州大学独墅湖校区403号楼一楼3119会议室

报告人简介：

Assistant Professor, Biological Science, Florida State University.

工作经历

2006–present Assistant Professor, Biological Science, Florida State University. Research, teaching, and services.

2006–present Graduate Faculty, Molecular Biophysics, Florida State University.

2000–2006 Postdoctoral Associate, Department of Embryology, HHMI/Carnegie Institution, Baltimore, MD. Research focus: Condensin and cohesin functions in meiotic chromosome organization. Surprised Johns Hopkins University undergraduate student Rizwan Ahmad conducting research.

1997–2000 Research Assitant, Plant Biology, University of Georgia. Research focus: Structure and function of the plant kinetochore. Supervised undergraduate student Lisa Reed conducting research.

1995–1998 Teaching Assistant, Plant Biology, University of Georgia. Courses: Botany 101 Lab and Biology 103 Lab.

1992–1995 Research Assistant, Shanghai Institute of Plant Physiology, Chinese Academy of Sciences. Research focus: Lipid composition and plant cold resistance.

荣誉和奖励

Normination of a University Undergraduate Teaching Award, Florida State University (2010).

New Investigator Research Grantee, Florida Biomedical Research Program (2008).

Basil O'Connor Starter Scholar, March of Dimes Foundation (2008).

First-Year Assistant Professor Award, Florida State University (2007)..

Wilbur Duncan Award, Department of Plant Biology, University of Georgia (1999).

Excellence in Graduate Student Research Award, University of Georgia (1999).

机构任职

American Association for the Advancement of Science

Golden Key International Honour Society, honorary member

The American Society for Cell Biology

近五年发表的论文

1、Li, P., Jin, H., & Yu, H.-G. (submitted 2011). Distinct roles of condensin in suppression of meiotic recombination and requirement for DNA double-strand break repair in budding yeast meiosis.

2、Goering, M., Yu, H.-G., Koshland, D., & Gerton, J. L. (submitted 2010). Loss of Mcd1 cohesin increases meiotic recombination frequency at coldspots in S. cerevisiae.

3、Shirk, K., Jin, H., Giddings,T. H., Winey, M., & Yu, H.-G. (2011). The Aurora kinase Ipl1 protects spindle pole body cohesion during yeast meiosis. Journal of Cell Science, in press.

4、Lin, W., Jin, H., Hampton, K., Liu, X., & Yu, H.-G. (2011). Scc2 regulates gene expression by recruiting cohesin to the chromosome as a transcriptional activator during yeast meiosis. Molecular Biology of the Cell, 22, doi:10.1091/mbc.E10.

5、Lin, W., Wang, M., Jin, H., & Yu, H. G. (2011). Cohesin plays a dual role in gene regulation and sister-chromatid cohesion during meiosis in Saccharomyces cerevisae. Genetics, 187, 1041–1051.

6、Brito, I. L., Yu, H.-G., & Amon, A. (2010). Condensins promote coorientation of sister chromatids during meiosis I in budding yeast. Genetics, 185, 55–64.

7、Jin, H., Guacci, V., & Yu, H.-G. (2009). Pds5 is required for homologue pairing and inhibits synapsis of sister chromatid during yeast meiosis. Journal of Cell Biology, 186, 713–725.

8、Macy, B., Wang, M., & Yu, H.-G. (2008). The many faces of shugoshin, the "guardian spirit," in chromosome segregation. Cell Cycle, 8, 35–37.