报告题目：有丝分裂的表观遗传信息
Mitotic inheritance of epigenetic information
报告人: 北京生命科学研究所高级研究员 朱冰
报告时间: 2012年4月24日（周二）下午2：00
报告地点: 苏州大学独墅湖校区医学楼403-3119会议室
报告人简介：
朱冰，北京生命科学研究所高级研究员朱冰，2002-2006年在Howard Hughes Medical Institute （Dr. Danny Reinberg）做博士后研究，2006年回国后短短数年在Science、EMBO Rep、Stem Cells、JBC等国际著名期刊上发表一系列高水平的论文，2012年获得HHMI青年科学家奖。
近五年发表的论文：
1. Xu M, Wang W, Chen S, Zhu B. A model for mitotic inheritance of histone lysine methylation. EMBO Rep. 2012; 13: 60-67.
2. Wang W, Mao Z, Zhang H, Ding X, Chen S, Zhang X, Zhu B. Nucleolar protein Spindlin1 recognizes H3K4me3 and facilitates rRNA gene transcription. EMBO Rep. 2011; 12: 1160-1166.
3. Yang P, Wang Y, Chen J, Li H, Kang L, Zhang Y, Chen S, Zhu B, Gao S. RCOR2 is a subunit of the LSD1 complex that regulates ES cell property and substitutes for SOX2 in reprogramming somatic cells to pluripotency. Stem Cells. 2011; 29: 791-801.
4. Chen X, Xiong J, Xu M, Chen S, Zhu B. Symmetric modification within a nucleosome is not globally required for histone lysine methylation. EMBO Rep. 2011; 12: 244-251.
5. Yuan W, Xu M, Huang C, Liu N, Chen S, Zhu B. H3K36 methylation antagonizes PRC2 mediated H3K27 methylation. J Biol Chem. 2011; 286: 7983-7989.
6. Wu H, Chen X, Xiong J, Li Y, Li H, Ding X, Liu S, Chen S, Gao S, Zhu B. Histone methyltransferase G9a contributes to H3K27 methylation in vivo. Cell Res. 2011; 21: 365-367.
7. Xu M, Long C, Chen X, Huang C, Chen S, Zhu B. Partition of histone H3-H4 tetramers during DNA replication-dependent chromatin assembly. Science 2010; 328: 94-98.
8. Jia G, Wang W, Li H, Mao Z, Cai G, Sun J, Wu H, Xu M, Yang P, Yuan W, Chen S, Zhu B. A systematic evaluation of the compatibility of histones containing methyl-lysine analogues with biochemical reactions. Cell Res. 2009; 19: 1217-1220.
9. Yuan W, Xie J, Long C, Erdjument-Bromage H, Ding X, Zheng Y, Tempst P, Chen S, Zhu B, Reinberg D. Heterogeneous nuclear ribonucleoprotein L Is a subunit of human KMT3a/Set2 complex required for H3 Lys-36 trimethylation activity in vivo. J Biol Chem. 2009; 284:15701-15707.
10. Moniaux N, Nemos C, Deb S, Zhu B, Dornreiter I, Hollingsworth MA, Batra SKThe human RNA polymerase II-associated factor 1 (hPaf1): a new regulator of cell-cycle progression. PLoS One. 2009；4: 470-77.
Pavri R, Zhu B, Li G, Trojer P, Mandal S, Shilatifard A, Reinberg D. Histone H2B monoubiquitination functions cooperatively with FACT to regulate elongation by RNA polymerase II. Cell. 2006; 125: 703-717.
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(基础医学与生物科学学院)
