报告题目:Understanding Sox9 Transcription Networks in Chondrogenesis
报 告 人:Xinjun He博士美国哈佛大学
报告地点:703楼1楼生物钟研究中心会议室
报告人简介:
Xinjun He博士,2005年毕业于清华大学生物系,获学士学位,2010年在美国俄勒冈大学获博士学位。2010年至今,哈佛大学博士后。He xinjun博士主要以斑马鱼为研究对象,在骨骼发育、贫血症、小RNA调控及生物信息学等领域取得了多项重要的研究成果。在nature genetics, developmental biology,PloS genetics等杂志上发表多篇高水平学术论文。
代表性论文:
Nakamura, Y. He, X.*, Kato, H. Wakitani, S., Kobayashi, T., Watanabe, S., Iida, A., Tahara, H.,Warman, M.L., Watanapokasin, R., Postlethwait, J.H. (2012) Sox9 Is Upstream of MicroRNA-140 in Cartilage. ApplBiochemBiotechnol.166(1):64-71. * Co-first author of this paper.
He, X., Yan, Y-L., Eberhart, J.K., Herpin, A., Wagner, T.U., Schartl, M., Postlethwait, J.H. (2011) miR-196 regulates axial patterning and pectoral appendage initiation. Dev Biol. 15;357(2):463-77.
Nakamura, Y., Yamamoto, K., He, X., Otsuki, B., Kim, Y., Murao, H., Soeda, T., Tsumaki, N., Deng, J.M., Zhang, Z., Behringer, R.R., Crombrugghe, B., Postlethwait, J.H., Warman, M.L., Nakamura, T., Akiyama, H. (2011) Wwp2 is essential for palatogenesis mediated by the interaction between Sox9 and mediator subunit 25.Nat Commun.2:251
Eberhart, J.K.*, He, X.*, Swartz, M.E., Yan, Y-L., Song, H., Boling, T.C., Kunerth, A.K., Walker, M.B., Kimmel, C.B., Postlethwait, J.H. (2008) MicroRNA Mirn140 modulates Pdgf signaling during palatogenesis. Nat Genet. 40(3):290-8. * Co-first authors of this paper
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