报告题目：Setting the Circadian Clock
报告人：张珞颖，PhD , Department of Neurology， University of California, San Francisco
报告时间： 2013年4月26日 （星期五）上午9:30-10：30 AM
报告地点：独墅湖校区703楼5层3502唐氏血液学研究中心会议室
报告人简介：
2003年在北京大学生命科学院获得学士学位；2009年在美国西北大学（Northwestern University）Ravi Allada实验室获博士学位。2010年到现在美国加州大学旧金山分校Ying-Hui Fu和Louise Ptacek实验室从事博士后研究。主要研究果蝇、小鼠以及人的生物钟调节机制。代表性论文发表在《PNAS》、《Current Biology》、《Neuron》、《Plos Biology》等著名刊物。
代表论文：
1.Zhang L, Ptacek LJ, Fu YH (in press) Diversity of Human Clock Genotypes and Consequences. Prog Mol Biol Transl Sci. (invited review)
2.Zhang L, Abraham D, Lin ST, Oster H, Eichele G, Fu YH, Ptacek LJ (2012) PKCγ Participates in Food Entrainment by Regulating BMAL1. Proc Natl Acad Sci USA 109,20679-20684.
3.Kategaya LS, Hilliard A, Zhang L, Asara JM, Ptacek LJ, Fu YH (2012) Casein kinase 1 proteomics reveal prohibitin 2 function in molecular clock. PLoS ONE 7, e31987.
4.Zhang L, Jones CR, Ptacek LJ, Fu YH (2011) The genetics of the human circadian clock. Adv Genet 74, 231-247. (invited review,兼通讯作者)
5.Chen Y, Dai H, Chen S, Zhang L, Long M (2011) Highly tissue specific expression of Sphinx supports its male courtship related role in Drosophila melanogaster. PLoS ONE 6, e18853.
6.Zhang L, Chung BY, Lear BC, Kilman VL, Liu Y, Mahesh G, Meissner RA, Hardin PE, Allada R (2010) DN1(p) circadian neurons coordinate acute and PDF inputs to produce robust daily behavior in Drosophila. Curr Biol 20, 591-599.
7.Zhang L,
8.Lear BC, Zhang L, Allada R (2009). The neuropeptide PDF acts directly on evening pacemaker neurons to regulate multiple features of circadian behavior. PLoS Biol 7,e1000154.
9.Kilman V, Zhang L, Meissner RA, Burg E, Allada R (2009) Perturbing dynamin reveals potent effects on the Drosophila Circadian Clock. PLoS ONE 4, e5235.
10.Lear BC, Merrill CE, Lin J-M, Schroeder A, Zhang L, Allada R (2005) A G-Protein Coupled Receptor, groom-of-PDF, Is Required for PDF Neuron Action In Circadian Behavior. Neuron 48, 1-7.
生物钟研究中心
(科研办公室)
