报告题目:Molecular and physiological mechanisms of circadian clocks in mammals
报告人:Prof. ANDREW CHUAN-YIN LIUUniversity of Memphis
报告时间:2014年11月18日10:00 AM
刘教授1992年本科毕业于山东师范大学生物学专业,1995年获中国科学院分子生物学硕士学位,2003年获密歇根大学医学院博士学位,2003年到2006年在美国加州斯克里普斯研究所进行博士后研究。2006年至今为孟菲斯大学助理教授,副教授(http://umdrive.memphis.edu/acliu/www/index.html)。刘教授主要的研究方向为哺乳动物生物钟调控的机制,主持了包括NIH RO1在内的多项研究基金,在Cell, Molecular Cell, Nature Chemical Biology, PNAS, PLoS Biology, PLos Genetics, 等国际一流期刊上发表论文30多篇。
本次报告刘教授将展示其在生物钟与高血压、生物钟蛋白相互作用机制方面的研究进展,欢迎大家光临。
代表性论文:
Liu AC*, Welsh DK* (co-first author), Ko CH, Tran HG, Zhang EE, Priest AA, Buhr ED,Singer O, Meeker K, Verma IM, Doyle FJ, Takahashi JS, Kay SA (2007) Intercellularcoupling confers robustness against mutations in the SCN circadian clock network. Cell 129:605-616
Liu AC, Lewis WG, Kay SA (2007) Mammalian circadian signaling networks and therapeutictargets. Nature Chemical Biology. 3 (10): 631-640
Zhang EE*, Liu AC* (co-first author), Hirota T*, Miraglia LJ, Welch G, Pongsawakul PY, LiuX, Atwood A, Huss JW, Janes J, Su AI, Hogenesch JB* and Kay SA* (2009) A Genome-widesiRNA screen for modifiers of the circadian clock in human cells. Cell 139: 199-210
Ukai-Tadenuma M, Yamada R, Xu H, Ripperger JA, Liu AC and Ueda HR (2011) Delay infeedback repression by Cry1 is required for circadian clock function. Cell 144: 268-281
Ramanathan C, Xu H, Khan SK, Shen Y, Gitis PJ, Welsh DK, Hogenesch JB, and Liu AC(2014) Cell type-specific functions of Period genes revealed by novel adipocyte andhepatocyte circadian clock models. PLoS Genet 10(4): e1004244
(学部办公室)

