Title：What wakes us? Networked circadian clocks in the brain Presenter：ERIK D. HERZOG, Ph.D. Professor, Washington Univ, Dept. of Anatomy and Neurobiology
Education
?1989-1994 Syracuse University, Institute for Sensory Research , Ph.D. in Neuroscience, with Robert Barlow
?1984-1987 Duke University BA in Biology & BA in Spanish, cum laude, with distinction in Biology
Research Description Dr. Herzog’s lab focus on the roles of the suprachiasmatic nucleus (SCN) and the olfactory bulbs (OB) in mammalian circadian rhythms. Including:
1.To study the circadian properties of cells in isolation, in small networks, and from different brain and body tissues in vivo and in vitro;
2.To examine the intracellular and intercellular processes that are involved in rhythm generation, synchronization to the environment, synchronization among oscillators and rhythmic output by combining behavioral assays, cell culture, electrophysiological and molecular techniques.
Related Papers:
1.Miller JE*, Granados-Fuentes D*, Wang T, Marpegan L, Holy TE, Herzog ED (2014). Vasoactive intestinal polypeptide mediates circadian rhythms in mammalian olfactory bulb and olfaction. J Neurosci. 34:6040-6. PMC3996221.
2.Bedont JL, Legates TA, Slat EA, Byerly MS, Wang H, Hu J, Rupp AC, Qian J, Wong GW, Herzog ED, Hattar S, and Blackshaw S (2014) Lhx1 controls terminal differentiation and circadian function of the suprachiasmatic nucleus. Cell Rep 7:609-22.
3.Ananthasubramaniam B, Herzog ED, Herzel H (2014) Timing of neuropeptide coupling determines synchrony and entrainment in the mammalian circadian clock. PLoS Comput Biol. 10:e1003565. PMC3990482.
4.An S, Harang R, Meeker K, Granados-Fuentes D, Tsai CA, Mazuski C, Kim J, Doyle FJ 3rd, Petzold LR, Herzog ED (2014) A neuropeptide speeds circadian entrainment by reducing intercellular synchrony. Proc Natl Acad Sci U S A. 2013 Nov 12;110(46):E4355-61. PMCID 3832006.
报告时间：2014年12月9日 10:00 AM
报告地点：703楼五层报告厅
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